Company Profile

Marine biotechnology+ Chito-oligosaccharides biological enzymatic preparation and purification technology

Provide customers with marine Chito-oligosaccharides and their derivatives product process services

Company Profile

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Heze Xinhai Biotechnology Co., Ltd

Heze Xinhai Biotechnology Co., Ltd, located in Luxi New District, Heze City, Shandong Province, is the source manufacturer of Chito-oligosaccharides with an annual production capacity of 100 tons. The company mainly provides Chito-oligosaccharides, chitosan oligosaccharides, chitosan and its derivatives, carboxymethyl chitosan, water-soluble chitosan, high and low density chitosan, and high-purity chitosan production and sales; R&D, production, processing and sales of marine biological products; production and sales of food additives and fodder additives; R&D, transfer of technological achievements and related technical services for biological extracted products, biological materials, animal and plant disease resistance and production enhancement products; Import and export of general goods and technology.

Heze Xinhai Biotechnology Co., Ltd

Our products:

Chito-oligosaccharide for food
Chito-oligosaccharide for food
Feed grade chito-oligosaccharides
Feed grade chito-oligosaccharides
Agriculture-grade chito-oligosaccharides
Agriculture-grade chito-oligosaccharides

Product application

Heze Xinhai Biotechnology Co., Ltd is a China-based company that develops, manufactures and sells marine Chito-oligosaccharides and its derivative product solutions. With innovative marine biotechnology solutions and efficient Chito-oligosaccharides biological preparation and purification technology, our Chito-oligosaccharides product solutions provide high-purity and high-precision pure natural chitosan oligosaccharides, which have the advantages of low molecular weight, good water solubility, large functional effect, easy absorption by the human body, and high biological activity. At the same time, it has the characteristics of pure natural, no radiation, no pollution, no additives and so on.

Chito-oligosaccharides, which processes polymer chitosan into water-soluble low molecules by the original microwave physical method, is a new biotechnology after genetic engineering and protein engineering, known as the third generation of biotechnology, which can be widely used in medicine, agriculture, food, chemical industry, energy, environmental protection, and other fields.

Pharmaceutical field

It plays an important role in the body's immune regulation, anti-tumor, hypolipidemic and blood sugar regulation, improvement of liver, cardiopulmonary function and other physiological functions.

Daily chemical industry

Chito-oligosaccharides physiological function

Regulates intestinal microbiota

Under acidic conditions, the free amino matrix protonation in Chito-oligosaccharides molecules, protonation can interact with the positively charged cell membrane of bacteria, interfere with the function of bacterial cell membranes, cause cytoplasmic loss in bacteria, and inhibit the growth of fungi and microorganisms. Its antibacterial activity is related to the strain and concentration, and its antibacterial activity is enhanced with the increase of concentration, and it has bactericidal effect when the concentration is high.

Chito-oligosaccharide is an important species of BF, which can regulate the metabolic activities of microorganisms in the intestinal tract of animals, improve the distribution of intestinal microflora, promote the growth and reproduction of bifidobacteria, thereby improving the body's immunity, reducing the pH in the intestine, inhibiting the growth of harmful bacteria in the intestine, producing B vitamins, decomposing carcinogens, promoting intestinal peristalsis, and improving protein absorption.

Improves intestinal tissue morphology

Improving the performance of animals Chito-oligosaccharides increases the density of ileal microvilli and also has a tendency to become thinner and taller. The increase in the height and density of microvilli is conducive to increasing the absorption area of the small intestine, promoting the absorption of nutrients, and improving the utilization of fodder.

Boosts immune function

The immune-enhancing effect of chito-oligosaccharides has been confirmed by many scholars, and its anti-infective mechanism is as follows: Chito-oligosaccharides stimulates the body, promotes the increase of the number of cells in peritoneal exudate, activates macrophages, thereby increasing the production of reactive oxygen species, and then acts through oxidative bactericidal mechanisms; The direct activation of macrophages by Chito-oligosaccharides increases the killing activity of macrophages; Chito-oligosaccharides activated T lymphocytes and showed killing activity, and sensitized T cells induced delayed hypersensitivity reactions. Chito-oligosaccharides activate T lymphocytes, which in turn induce the release of macrophage activating factor (MAF), which in turn activates macrophages. During activation, macrophages are directly activated by Chito-oligosaccharides, which increases their sensitivity to MAF and further activates them. Therefore, it is believed that the production of the killing activity of Chito-oligosaccharides is mainly the result of the enhanced interaction between activated T lymphocytes and macrophages.

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